SANTA CLARA — The 49ers went a lackluster 2-2 in the season's proverbial "first quarter." Still to come are 12 games, only three of which are against teams currently with a winning record.
Those upper-echelon foes are the Tennessee Titans (3-1; host the 49ers on Oct. 20), the New Orleans Saints (3-0; host 49ers on Nov. 17) and the Seattle Seahawks (4-0; visit 49ers on Dec. 8).
All other opponents have one or no wins, except for the Arizona Cardinals (2-2) and Houston Texans (2-2).
Here is a glimpse at the remaining regular-season schedule:
Oct. 6, vs. Houston: The Texans blew a 20-3 lead at home Sunday against the Seahawks, who maintained a two-game lead on the 49ers in the NFC West. Matt Schaub has thrown a pick-six in three straight games. Linebacker Brian Cushing must pass a post-concussion test to be cleared for Sunday night's game at Candlestick.
Oct. 13, vs. Arizona: Sunday's win at vulnerable Tampa Bay leveled out the Cardinals' record, as they've only played one home game thus far.
Oct. 20, at Tennessee: The Titans may not have starting quarterback Jake Locker, who sustained a hip injury in Sunday's win over the New York Jets that could sideline him a month, according to The Tennesseean's Jim Wyatt.
Oct. 24, at Jacksonville (in London): The 49ers should be heavy favorites in Wembley Stadium when they play the back end of their two-game road trip, and do so against likely the NFL's worst team.
Nov. 3: Bye
Nov. 10, vs. Carolina: Idle last weekend, the Panthers are hoping their Sept. 22 win over the New York Giants still offers enough momentum to carry them to their first winning season since 2008.