Kaepernick's career-worst game from a statistical standpoint came in that Week 2 loss at Seattle, when he was was 13-of-28 for 127 yards with no touchdowns, three interceptions and a 20.1 passer rating.
"Home-field advantage is always a big thing," Kaepernick said of playing in San Francisco rather than the loud CenturyLink Field. "You get to use cadence and audibles you can't use on the road if you can't hear."
Kaepernick conducted his weekly press conference in the locker room corner that houses his offensive linemen, many of whom rolled their eyes when he brought the 30-reporter cluster into their domain. Alex Boone, who might start at left tackle in place of the injured Joe Staley, told Kaepernick he would be fined for invading their space with media.
Asked why it seems he despises press conferences, Kaepernick replied: "I signed a contract to play football. The media is just an obligation I have to do."
SEATTLE CB COULD RETURN
Seahawks coach Pete Carroll said Wednesday the club is still awaiting word on any possible discipline coming for cornerback Brandon Browner, who might be healthy enough to return to practice this week.
"I don't know. We have no control over it," Carroll said. "We don't know. We have no timeline. We're just waiting to get him ready. He's healthy enough to get back on the field some and we'll see how it goes."
Carroll said that Browner has progressed quicker than expected from a groin injury suffered in Week 10 at Atlanta. At first it appeared to be at least a six-week injury, Carroll said, but Browner has responded to treatment faster than first believed.
As for a possible suspension awaiting Browner, Carroll said the team has no idea when word might be coming from the NFL.
"Early on we couldn't tell you about the injury because he had a significant groin tear but he managed it really well and it was in a place that we found out he could recover quickly. We thought he was out a solid six weeks when it happened," Carroll said. "He's just responded tremendously. He's on the roster and he's ready to compete for us if he can get back to practice this week. We'll do this one day at a time and we'll see where it fits."
Seattle is thin in the secondary with Browner injured and Walter Thurmond serving a four-game suspension for violating the league's substance-abuse policy. Byron Maxwell and Jeremy Lane filled in for the pair and played well in the Seahawks' 34-7 win over New Orleans on Monday night.
Carroll also said he was unsure if Percy Harvin would be healthy enough to play Sunday at San Francisco. Harvin didn't play in Monday night's win over New Orleans as he continued to have soreness in his surgically repaired hip after making his season debut in Week 11 against Minnesota.
Carroll said Harvin has been treated for the inflammation in the hip but that it's unknown when he will return to the field.
49ERS' OFFENSIVE LINE WOES
A little-known offensive lineman with less than one full game of NFL experience could find himself starting for San Francisco in its biggest game of the year yet.
Every Sunday, Joe Looney goes through his own pregame practice on the Candlestick Park field well before his 49ers teammates on the active roster do it for real. Such is life on the practice squad, or development squad as it is called around here.