The 10 sacks were a factor in the game. The interceptions made the difference.
The Chiefs (6-0) and Raiders were tied 7-all in the third quarter when Pryor threw the first of his picks, a rainbow off his back foot into the middle of the field. Jamaal Charles finished off the drive with his second touchdown run to give Kansas City its first lead of the game.
The second interception came as the Raiders (2-4) were trying to drive for a tying score, and this time the Chiefs' Ryan Succop kicked a 33-yard field goal late in the fourth quarter.
Husain Abdullah returned the final pick 44 yards for a touchdown with 1:35 left in the game.
"We were right there in the game and we were punching back and forth," Pryor said. "We turned the ball over, and like I said, I lost the game for us. I'm going to fall a lot, but I'm going to get up. That's how it is. I'm going to get up and I'm going to come swinging."
The Chiefs, meanwhile, pressed on with the second-best start in franchise history after winning just twice last season. They won their first nine games during the 2003 season.
They wound up sacking Pryor 10 times, and ended a three-game skid to the Raiders.
"We don't take any wins for granted. That's not how we operate," Chiefs coach Andy Reid said. "We're going to enjoy every one of these, and we'll come back and be ready to go next week."
Chiefs fans were hoping to break the record for loudest outdoor sports stadium, set earlier this year by the Seahawks. They finally did it in the closing seconds of the game when they hit 137.5 decibels, an official from Guinness World Records told The Associated Press.
Pryor and his patchwork offensive line struggled to deal with the crowd noise, especially in the second half.
On one possession, Pryor was twice whistled for delay of game penalties partly because third-string center Mike Brisiel couldn't hear him. Oakland also had a false start on the same drive.
The Raiders finished with 11 penalties for 68 yards.
"It was a factor in the game," Allen said of the crowd. "Obviously we had some trouble getting in and out of the huddle. We had some trouble with snap-count communication."
Oakland actually struck first in the second quarter when Denarius Moore beat Chiefs defensive back Marcus Cooper, starting in place of the injured Brandon Flowers, on a quick slant over the middle. Moore caught the pass from Pryor in stride and went 39 yards for the touchdown.
It remained 7-0 until the waning minutes of the first half, when the Chiefs took over at the Oakland 45. Pass interference on the Raiders' D.J. Hayden on third-and-10 kept the drive alive, and Charles squirmed the 7 yards for the tying score with 1:06 left.
"The key thing was to get something going before halftime," Chiefs quarterback Alex Smith said.